Upon hearing gurgling in the upper airway while ventilating with a bag-mask device, you should:

When gurgling is heard in the upper airway during ventilation with a bag-mask device, it typically indicates the presence of fluid in the airway, such as vomit or secretions. The most appropriate response is to position the patient onto their side. This maneuver helps facilitate the drainage of any fluids out of the airway, reducing the risk of aspiration and allowing for more effective ventilation.

This lateral positioning also enables gravity to assist in clearing the airway, making it easier to suction any obstructions if necessary afterward. The other options, while they may have their place in airway management, do not specifically address the immediate concern of fluid in the airway as effectively as repositioning the patient.